Animal models have been extensively used to understand the biological mechanisms of OTM. However, rodent models have disadvantages, including a reported reduction in bone volume during OTM. This presentation will answer the following questions: What was the success rate of skeletal anchorage in a rodent OTM model? What was the effect of a low force (~3cN) on inter-radicular bone volume during OTM in a rodent? What was the amount of tooth movement obtained at different time points with ~3cN force?
Demonstrate that skeletal anchorage offers important advantages in obtaining an appropriate force vector, minimizing animal husbandry and personnel time, and achieving predictable and efficient tooth movement in a rodent OTM model.
Demonstrate that there was no dramatic reduction in BV/TV with the application of low forces.
Validate an OTM model in rats with skeletal anchorage and low calibrated forces.